Cost-optimisation of screening for latent tuberculosis in close contacts
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چکیده
We read with great interest the article by DIEL et al. [1] in a recent issue of the European Respiratory Journal. We believe that the authors have been successful in modelling and analysing the cost of alternatives for tuberculosis (TB) contact investigation. Nevertheless, we have some hesitation regarding a simplifying assumption that the authors have made in the follow-up of subjects after a positive screening test.
منابع مشابه
Management of Latent Tuberculosis in Iran
Although screening, finding and treatment of active cases of tuberculosis is very important for control of disease in the community, for reaching to the goals planed by world health organization and approaching to elimination of the disease, it is necessary to find and treat persons with latent infection. Concerning to high prevalence of latent TB in developing countries and resource limitation...
متن کاملCost-optimisation of screening for latent tuberculosis in close contacts.
The aim of the present study was to perform cost-minimisation analysis of contact investigation from a public health perspective using the tuberculin skin test (TST) and a new blood assay, QuantiFERON-TB Gold (QFT-G). A decision-analysis model simulated the costs of investigating a cohort of adult close tuberculosis contacts by the public health service following the current German guidelines o...
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The aim of the present study was to assess the cost-effectiveness of the new T-SPOT.TB assay versus the tuberculin skin test (TST) for screening contacts for latent tuberculosis (TB) infection in Switzerland. Health and economic outcomes of isoniazid treatment of 20- and 40-yr-old close contacts were compared in a Markov model over a 20-yr period following screening with TST only (at three cut-...
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One of the recommended strategies for preventing tuberculosis is to screen high-risk populations with respect to Mycobacterium tuberculosis (TB) infection. The aim of the present study was to investigate latent infection and active tuberculosis in people with close household contact. It was a cross-sectional descriptive, analytical study with the sample size of 668 people from homes with one in...
متن کاملInterferon-gamma release assays and TB screening in high-income countries: a cost-effectiveness analysis.
OBJECTIVE Interferon-gamma release assays (IGRA) are now available alternatives to tuberculin skin testing (TST) for detection of latent tuberculosis infection (LTBI). We compared the cost-effectiveness of TST and IGRA in different populations and clinical situations, and with variation of a number of parameters. METHODS Markov modelling was used to compare expected TB cases and costs over 20...
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تاریخ انتشار 2006